What Causes Wrinkles?

In younger skin, cells called fibroblasts are highly active, producing a rich, organised matrix of collagen and elastin. As we age, these fibroblasts naturally slow down, and specific enzymes (called MMPs) begin to break down existing collagen faster than it is replaced. This gentle shift in your skin’s deep structural matrix is what creates the fine lines and wrinkles that map your life's journey.

What Causes Loss of Firmness?

Think of healthy elastic fibres like tiny rubber bands that help your skin snap back. But with cumulative sun exposure, UV rays can alter how our cells function, causing our fibroblasts to produce less resilient elastin. Instead of clean, recoil-ready fibres, the elastin accumulates into a disorganised network. This structural change reduces the skin's ability to bounce back, leading to a natural relaxation or sagging.

What Causes Uneven Skin Tone?

A vibrant, healthy glow comes from a fast, efficient cell turnover rate, where young skin cells (keratinocytes) quickly move to the surface and shed in a uniform rhythm (desquamation). As this renewal cycle naturally paces itself over time, these older cells can gather and pile up unevenly on the skin's surface. This irregular layer scatters light poorly, making your complexion look a less radiant.

What Weakens the Skin Barrier?

It helps to think of your skin’s protective surface like a brick-and-mortar wall. The cells (corneocytes) are the 'bricks', and the essential lipid bilayer made of ceramides, cholesterol, and fatty acids acts as the 'mortar'. Over time, these cellular bricks can become disorganised, and the essential lipids are gradually depleted. This natural shift in the skin's architecture makes it a little easier for essential hydration to escape and for everyday irritants to slip in.

Tested at the Cellular Level — The Manchester Patch Test Assay

The Process: Intra-subject controlled, double-blinded study on human volunteers with skin biopsies taken and biomarkers examined under microscope. Validated & bench-marked against prescription product. The Purpose: Rapidly models 6 months of use on live human skin. The Results: Outperformed gold standard (equivalent 20x more effective than retinol). 2x increase in collagen. 2x increase in fibrillin.

Measured on the Surface — Clinical Trial

The Process: 29 people have baseline professional Visioscan in controlled conditions to measure wrinkle depth, images are taken before using the product, at 7 days, 4 weeks and 12 weeks. Computer-measured wrinkles are compared to the baseline. The Purpose: A good study to see if visual improvements are obtained from use of the product. The Results: Significant reduction in wrinkles with statistical significance of p=0.0004 in as little as 7 days.

Perceived in the Mirror — Consumer Trial

The Process: 44 people are provided with the product to use for 12 weeks, volunteers are asked questions about their experience at 0, 4, and 12 weeks. The Purpose: This study is useful to understand volunteers' experience from product use, while it lacks rigorous scientific credentials, it helps to ensure that a person's experience aligns with the scientific results. The Results: 98% gentle 93% nourished 93% healthier 86% fine lines reduction 86% more youthful 93% no irritation

1 10

Night Repair Therapy

178 total reviews

Multi-award winning night cream proven to be 20x more effective than retinol - Without the irritation.

Visibly reduces fine lines and wrinkles
Restores skin firmness & elasticity
Created by world-renowned Prof. Chris Griffiths OBE.

Earn 675 Skin Health Club points

Or 3 payments of £45.00 GBP with

18+, T&C apply, Credit subject to status.

MULTI-AWARD WINNING RESULTS

View full details

Night Repair Therapy

£135.00 GBP

KEY BENEFITS

Reduces Fine Lines & Wrinkles

Clinically proven to reduce fine lines and wrinkles in 7 days^[1]

Improves Skin Firmness & Elasticity

2x increase in collagen & elastic fibres^[2]

Improves Skin-Tone & Texture

Increases skin cellular turnover^[3]

Renews & Strengthens Skin Barrier

20x more effective than retinol in a non-irritating formula^[4]

View Citations

[1] Proven in independent clinical study of 29 people that found a significant reduction in wrinkles with statistical significance of p-value = 0.0004[2] Proven in independent study at University of Manchester via the Manchester Patch Test Assay[3] Mukherjee S, et al. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-48.[4] Proven in independent study at University of Manchester. Tested vs prescription gold standard equiv 20x more efficacious than retinol.

As Featured In

BEFOREAFTER 12 WEEKS
BEFOREAFTER 12 WEEKS
BEFOREAFTER 12 WEEKS
BEFOREAFTER 12 WEEKS
BEFOREAFTER 12 WEEKS
BEFOREAFTER 12 WEEKS

1 6

PURE SCIENCE. PROVEN RESULTS

Proven Results

Rigorously tested across all three dimensions of our Cell-to-Surface™ standard

Tested at the Cell

BIOLOGICAL EFFICACY

2x Increase in collagen

2x Increase in elastic fibres

*Proven in independent Manchester Patch Test Assay at the University of Manchester

Measured on the Surface

CLINICAL STUDY

7 Days Significant reduction in wrinkles in as little as 7 days

Perceived in the Mirror

Consumer Validated

93% Said their skin looked healthier

86% Noticed a reduction in fine lines and wrinkles

INGREDIENTS

Born from Prof. Griffiths’ core belief: true skin health relies on synergy, not just isolated ingredients. By precisely pairing a highly tolerable retinyl-ester with cell-communicating peptides, antioxidants, and multi-molecular hyaluronic acid, he engineered a formula where the ingredients actively amplify one another.

Protect

Vaccinium Myrtillus Fruit Leaf Extract, Lycopene, Niacinamide

Bilberry extract: Inhibits free radical damage.

Hydrolysed tomato skin: Shields from photo-oxidative damage.

Niacinamide: Maintain healthy skin during environmental exposure.

Renew

Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Retinyl Palmitate

Cell-communicating peptides: Supports collagen synthesis.

Retinyl-ester: Promotes skin renewal and cell turnover.

Restore

Helianthus Annuus Seed Oil, Cocos Nucifera Oil, Theobroma Cacao Seed Butter, Prunus Amygdalus Dulcis Oil, Simmondsia Chinensis Seed Oil

Multimolecular hyaluronic acid: Supports the barrier & improves the performance of other ingredients.

Botanical oils: Support the lipid barrier & reduce inflammation.

View full INCI

Aqua, Helianthus Annuus Seed Oil, Cetyl Alcohol, Cetearyl Alcohol, Cocos Nucifera Oil, Glycerin, Theobroma Cacao Seed Butter, Prunus Amygdalus Dulcis Oil, Glyceryl Stearate, Simmondsia Chinensis Seed Oil, PEG-100 Stearate, Hydrolyzed Tomato Skin, Vaccinium Myrtillus Fruit/Leaf Extract, Butylene Glycol, Niacinamide, Hydrolyzed Hyaluronic Acid, Tocopherol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Retinyl Palmitate, Carbomer, Triethanolamine, Phenoxyethanol, Ethylhexylglycerin, Polysorbate 20, Sodium Lactate

HOW TO USE

How to Apply Your Night Repair Therapy

Night Repair Therapy is a concentrated formula, so a little goes a long way.

How to apply:

Use a pea-sized amount for the entire face and neck
Warm between fingertips, then gently smooth into the skin

When to use:

Apply every evening as the final step in your routine
Use after cleansing (and after any optional serums, if desired)

A Global authority in skin ageing

Created by Prof. Chris Griffiths OBE

Professor Chris Griffiths OBE is one of the world’s most distinguished consultant dermatologists, awarded an OBE in 2018 for his globally recognised services to dermatology.

Prof. Griffiths was part of the pioneering research team that first discovered exactly how topical retinoids repair the cellular structure of aged skin and has spent decades studying the biological mechanisms of skin ageing.

Night Repair Therapy is the culmination of this life’s work: a final formulation that harnesses his deep understanding of retinoid pathways to deliver clinical-grade repair, without the irritation.

DEEP RESULTS TAKE TIME TO BUILD

What to Expect

1 Week

THE SURFACE RESULT

You will notice a visible softening of fine lines and a smoother surface texture. It is important to know that these early changes are primarily driven by moisturisation and barrier repair.

1 Month

The first renewal cycle

As your skin completes its first natural 28-day turnover, the biological support begins. Your skin may feel softer to the touch, without the redness or flaking that can arise from retinol.

3 Months

The Clinical Milestone

This is when our clinical trials measured a statistically significant reduction in the appearance of deeper wrinkles, alongside a visibly healthier, more vibrant complexion.

6 Months

Profound, Lasting Health

Skincare is a long-term investment. By month six, your skin’s barrier and underlying structure are consistently supported. You will maintain a resilient, healthy barrier, sustained visible firmness, and an ongoing daily defence against the visible signs of ageing.

FAQs

Will Night Repair Therapy make my skin peel or dry out?

No. The formula is specifically designed to minimise irritation, including dryness or peeling. The retinyl ester used in Night Repair Therapy is a milder form of retinoid that offers all the powerful benefits without the irritation often associated with traditional retinoids.

Where can I buy Night Repair Therapy?

You can purchase Night Repair Therapy directly through our website. Click on the "Buy Now" button to start your journey to healthy, rejuvenated skin.

What type of clinical testing has been done on Night Repair Therapy?

Night Repair Therapy has undergone rigorous double-blind, placebo-controlled clinical trials in human skin. These studies demonstrated its ability to significantly increase collagen and elastin production, crucial for reducing wrinkles and improving skin firmness.

How do I use Night Repair Therapy?

Apply a pea-sized amount of Night Repair Therapy to cleansed skin in the evening, focusing on areas with visible signs of ageing.

Is Night Repair Therapy tested on animals?

No. Night Repair Therapy is cruelty-free and has not been tested on animals. Our commitment to ethical testing aligns with our goal to deliver results without compromising on quality or integrity.

How does Night Repair Therapy renew the skin?

The formula contains peptides and retinyl ester, which stimulate collagen and elastin production while promoting cellular turnover. Hyaluronic acid (in two different molecular weights) helps to maintain skin elasticity and moisture levels, providing a plump, youthful appearance.

What are the key ingredients in Night Repair Therapy?

Night Repair Therapy features a blend of peptides, retinyl ester, bilberry, hydrolysed tomato skin, two chains of hyaluronic acid. These ingredients work together to protect, renew, and restore the skin for optimal anti-ageing results.

Can I use Night Repair Therapy with other skincare products?

Absolutely. Night Repair Therapy easily integrates into your existing skincare routine or with our personalised routines: Chapters. Night Repair Therapy is best used after cleansing.

Is Night Repair Therapy suitable for sensitive skin?

Yes. Night Repair Therapy is designed to deliver powerful anti-ageing benefits without irritation, making it suitable for sensitive skin types. The unique formula combines active ingredients with soothing botanicals like bilberry and hydrolysed tomato skin to minimise risk of irritation.

How long does it take to see results with Night Repair Therapy?

You can expect to see visible improvements in your skin within 3 months of consistent use and continued improvement in the months following. Clinical studies show significant increases in collagen and elastin levels, which are key to reversing signs of ageing.

What makes Night Repair Therapy different from other anti-ageing creams?

Night Repair Therapy uses a unique three-step approach: protecting healthy cells, renewing damaged ones, and restoring the skin barrier. Unlike other retinoid products, it delivers results without irritation thanks to its carefully balanced blend of peptides, retinyl-ester, antioxidants, and advanced delivery mechanisms. It's been tested in double-blind, placebo-controlled clinical trials, ensuring its effectiveness.

I am sensitive to retinoids, will I be okay with Night Repair Therapy?

Our rigorous testing showed Night Repair Therapy to be well-tolerated for sensitive skin and retinoid sensitivity. However, everyone's skin is unique so if you're allergic to or have questions about specific ingredients, please reach out to our team who are happy to help.

Can I use Night Repair Therapy every night?

Yes, we encourage you to use it every night to see best results.

Can I use Night Repair Therapy while pregnant or breastfeeding?

Night Repair Therapy is not safe for breastfeeding due to the inclusion of retinoids in the formula.

Are all costmetic products tested on human skin?

No, many products aren't tested on human skin, which is why Night Repair Therapy is so unique.

How do I know it works?

By the rigorous testing we carry out. Night Repair Therapy has been held to the highest standard of scientific testing. Double-blind, placebo-controlled clinical studies in human skin.

5 stars: 154 (87%)
4 stars: 16 (9%)
3 stars: 3 (2%)
2 stars: 5 (3%)
1 star: 0 (0%)

Excellent, it really works!

After years of looking after my skin with good quality products including serums and retinal, my good friend introduced me to Skindiary. I’ve been using Night Therapy for over a year now and what a difference. My skin seems plumper, more hydrated and a more even skin tone. Yes, at 68 I have wrinkles and crepeness but these have diminished and softened. I no longer have powdery areas of dry skin, and make up goes on more smoothly. I’m now ordering the Day Therapy and looking forward to even more improvement.

THE only night cream I use!

I have tried many, many night creams over my 64 years but The Skin Diary is amazing. Just one product, I even use it under my eyes, at night and that’s it. Beautiful skin.

Really working for me

I am 59 with good skin that I’ve taken care of. My skin is dry through, with fine lines and over the last few years I’ve tried many moisturisers including the very expensive. Nothing has worked as well as Night Repair Therapy. My skin is plumped and glowing with a noticeable reduction in dark spots. I was considering Botox not now don’t think I need it. I’m about to order my third pot. I definitely recommend.

I love the feel

I love this Night Cream. I have used it for several weeks now and friends have commented on my skin appearance. I love in hope that my wrinkles round my mouth will lessen just a little. Nevertheless I pop on the cream each night and love the feel of it as I spread a little on my skin.

Great product, like a hug for your face

Great product, like a hug for your face. Beautiful texture, a little goes a long way! And it works, fine lines reduced, more even complexion, soft smooth skin.

It really is the best night cream I’ve ever used

It really is the best night cream I’ve ever used. It feels luxurious and my skin looks brighter and firmer.

Wonderful product

Wonderful product. My skin feels and looks better than it has ever done. And none of this messing around with serums. The one product seems to do it all

Love this cream so much

My skin is completely different after a few months of using Night Repair Therapy. I had such dry skin on the side of my forehead that no moisturiser seemed to help with but now that I use the skin diary regularly, it has completely disappeared. I absolutely recommend!

My skin loves this!

I’m 56 with dry skin and I absolutely love this stuff! I’m on my 3rd jar now and honestly can’t see me using anything else. The tone and texture of my skin is definitely improving. A really beautifully packaged indulgent product and I’m really enjoying using it every night.

Great product, my skin feels and looks great

Great product, my skin feels and looks great.

I have been using the night cream for well over a

I have been using the night cream for well over a year and wouldnt use anything else it really does what it says. I used to have mature dry skin but the night cream has changed all that, I wake up looking quite glowy can definitely recommend

I’m only on my first bottle of night repair and the day cream.

I’m only on my first bottle of night repair and the day cream. I’m enjoying using the products so far and before I invested I was going by the reviews so I hope it’s not just another skin care brand making promises, the main thing for me is the words ‘over time’ & I understand that as no cream is going to deliver instant miraculous results.
It’s an expensive investment but so far I’m cautiously optimistic.
Nicest products I’ve used so far & I will be re purchasing so……..

I use both creams and they are really effective

I use both creams and they are really effective. My skin just soaks up the goodness and stays feeling great. Honestly they’re expensive, but probably no
More than other creams where you need to use more. I’d highly recommend.

Luxurious!

First of all the packaging is so luxurious it makes it feel really expensive. The cream feels very rich and nourishing. I've been buying this item for about a year or more now, and I don't intend changing any time soon!

Amazing product

An amazing product. Used for 3 months now and there's certainly no going back.

Wonderful all in one night cream

Wonderful all in one night cream.

Love this

Love this night cream. Good results and my skin looks and feels a lot better. Also does help to soften wrinkles.

Best night cream on the market

We both have been using skin diary for 10months and honestly have thrown all our other products away
Love the thickness of the night cream and truthfully the research your team especially Tammy and Chris who I have known for 30years and trust that they have made the best product on the market.
The day cream absorbs really well and feel confident that I do need any additional spf.
Looking forward to the body cream and eye serum .

I have been using night repair for a month,

I have been using night repair for a month, and its great.my forehead creases are improving and overall texture of my skin, its a little jar of magic .definitely recommend.ps im very fussy, and skin care has always been important. X

Love this cream! Skin looks and feels more radiant and healthy.

Love this cream! Skin looks and feels more radiant and healthy. The cream feels amazing when you put it on and it soaks in really well so, unlike other night creams, you don't feel like half of it has come off onto your pillow! You only need a small amount so the pot lasts a long time.

Love Love this product There is nothing about

Love Love this product!
There is nothing about this product that I dislike!
Less products and great results a win win for me!
Thank you Team 😘
I have been using it now for about 18 months and my skin is glowing!

Excellent product skin is definitely changed for the better since using tjis cream nightly

Simple, and works. Skin feels food and no new wrinkles!!

Before I started with Skin Diary it was a mind field with products. I wanted anti wrinkle, skin smoothing , glowing skin, clear pores. In order for this i needed 4 different serums,.and some did not mix well together. One product, it may appear expensive but if you add serums and moisturiser you were using it may some in more expensive.

The Perfect Solution

I am on my second tub of Night Repair and 3rd tube of the Age Defence Day Cream and I love them. It is genius to have one cream for day and one for night and each having all of the elements you need. I attended a talk by Dr. Claire Kiely at the Future of Beauty Show in the RDS this March and it was fascinating to learn the purpose and the science behind all of the ingredients. I found the Age Defence a little drying on my face at first but once my skin became accustomed to it that went away. I would not use anything else. The price point does not bother me as a day / night cream plus all the other serums and SPF etc would easily amount to more that what those two products cost. I am looking forward to more product launches from The Skin Diary please!

Great product

I love the night repair cream. The texture is really nourishing but also soaks right into my skin. I’m really enjoying that I don’t have to use any other products. I’ve noticed visible difference in skin elasticity over the last few months

Cannot go without these products!

I have both day and night creams and would not be without them. As a woman in menopause my skin has suffered acne lines and dehydration. However for me personally these products have addressed all my issues. I see them as an investment as I continue to see my skin improve.

Hydrating without being heavy

Happy so far . I have dry skin and this keeps my skin hydrated without being heavy, absorbs well. I use it in the day with an added spf . I have not been using it long enough to see pronounced results but my skin texture has improved.

Love these and excellent service

Your cart is empty

Your cart

Estimated total

Night Repair Therapy