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Book a Chapters consultation

Book a Chapters consultation

Book an online Chapters consultation with our skin experts to discuss how you can reverse the signs of skin ageing with our Chapter routines.

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MULTI-AWARD WINNING RESULTS

30 Day Money Back Guarantee

Or 3 payments of £16.67 GBP with 18+, T&C apply, Credit subject to status.
Earn 250 Skin Health Club points
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Book a Chapters consultation

£50.00 GBP

KEY BENEFITS

Reduces Fine Lines & Wrinkles

Clinically proven to reduce fine lines and wrinkles in 7 days[1]

Improves Skin Firmness & Elasticity

2x increase in collagen & elastic fibres[2]

Improves Skin-Tone & Texture

Increases skin cellular turnover[3]

Renews & Strengthens Skin Barrier

20x more effective than retinol in a non-irritating formula[4]
View Citations
[1] Proven in independent clinical study of 29 people that found a significant reduction in wrinkles with statistical significance of p-value = 0.0004[2] Proven in independent study at University of Manchester via the Manchester Patch Test Assay[3] Mukherjee S, et al. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-48.[4] Proven in independent study at University of Manchester. Tested vs prescription gold standard equiv 20x more efficacious than retinol

A simulation of H&E stained histology of facial skin showing the skin structure of healthy skin and aged skin.

What Causes Wrinkles?

In younger skin, cells called fibroblasts are highly active, producing a rich, organised matrix of collagen and elastin. As we age, these fibroblasts naturally slow down, and specific enzymes (called MMPs) begin to break down existing collagen faster than it is replaced. This gentle shift in your skin’s deep structural matrix is what creates the fine lines and wrinkles that map your life's journey.

A simulation of VVG stained histology of facial skin showing the skin structure of healthy skin and aged skin.

What Causes Loss of Firmness?

Think of healthy elastic fibres like tiny rubber bands that help your skin snap back. But with cumulative sun exposure, UV rays can alter how our cells function, causing our fibroblasts to produce less resilient elastin. Instead of clean, recoil-ready fibres, the elastin accumulates into a disorganised network. This structural change reduces the skin's ability to bounce back, leading to a natural relaxation or sagging.

A simulation of Fontana-Masson stained histology of facial skin showing the skin structure of healthy skin and aged skin comparing cell turnover and the result to the surface.

What Causes Uneven Skin Tone?

A vibrant, healthy glow comes from a fast, efficient cell turnover rate, where young skin cells (keratinocytes) quickly move to the surface and shed in a uniform rhythm (desquamation). As this renewal cycle naturally paces itself over time, these older cells can gather and pile up unevenly on the skin's surface. This irregular layer scatters light poorly, making your complexion look a less radiant.

A simulation of Oil Red O stained histology of facial skin showing the skin structure of healthy skin and aged skin with a dry compromised skin barrier.

What Weakens the Skin Barrier?

It helps to think of your skin’s protective surface like a brick-and-mortar wall. The cells (corneocytes) are the 'bricks', and the essential lipid bilayer made of ceramides, cholesterol, and fatty acids acts as the 'mortar'. Over time, these cellular bricks can become disorganised, and the essential lipids are gradually depleted. This natural shift in the skin's architecture makes it a little easier for essential hydration to escape and for everyday irritants to slip in.

As Featured In

  • BEFOREAFTER 12 WEEKS
  • BEFOREAFTER 12 WEEKS
  • BEFOREAFTER 12 WEEKS
  • BEFOREAFTER 12 WEEKS
  • BEFOREAFTER 12 WEEKS
  • BEFOREAFTER 12 WEEKS
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PURE SCIENCE. PROVEN RESULTS

Proven Results

Rigorously tested across all three dimensions of our Cell-to-Surface™ standard

Tested at the Cell

BIOLOGICAL EFFICACY

2x Increase in collagen
2x Increase in elastic fibres

*Proven in independent Manchester Patch Test Assay at the University of Manchester

Measured on the Surface

CLINICAL STUDY

7 Days Significant reduction in wrinkles in as little as 7 days
Perceived in the Mirror

Consumer Validated

93% Said their skin looked healthier
86% Noticed a reduction in fine lines and wrinkles

INGREDIENTS

Born from Prof. Griffiths’ core belief: true skin health relies on synergy, not just isolated ingredients. By precisely pairing a highly tolerable retinyl-ester with cell-communicating peptides, antioxidants, and multi-molecular hyaluronic acid, he engineered a formula where the ingredients actively amplify one another.

Protect

Vaccinium Myrtillus Fruit Leaf Extract, Lycopene, Niacinamide

Bilberry extract: Inhibits free radical damage.

Hydrolysed tomato skin: Shields from photo-oxidative damage.

Niacinamide: Maintain healthy skin during environmental exposure.

Renew

Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Retinyl Palmitate

Cell-communicating peptides: Supports collagen synthesis.

Retinyl-ester: Promotes skin renewal and cell turnover.

Restore

Helianthus Annuus Seed Oil, Cocos Nucifera Oil, Theobroma Cacao Seed Butter, Prunus Amygdalus Dulcis Oil, Simmondsia Chinensis Seed Oil

Multimolecular hyaluronic acid: Supports the barrier & improves the performance of other ingredients.

Botanical oils: Support the lipid barrier & reduce inflammation.

View full INCI

Aqua, Helianthus Annuus Seed Oil, Cetyl Alcohol, Cetearyl Alcohol, Cocos Nucifera Oil, Glycerin, Theobroma Cacao Seed Butter, Prunus Amygdalus Dulcis Oil, Glyceryl Stearate, Simmondsia Chinensis Seed Oil, PEG-100 Stearate, Hydrolyzed Tomato Skin, Vaccinium Myrtillus Fruit/Leaf Extract, Butylene Glycol, Niacinamide, Hydrolyzed Hyaluronic Acid, Tocopherol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Retinyl Palmitate, Carbomer, Triethanolamine, Phenoxyethanol, Ethylhexylglycerin, Polysorbate 20, Sodium Lactate

HOW TO USE

How to apply Night Repair Therapy

How to Apply Your Night Repair Therapy

Night Repair Therapy is a concentrated formula, so a little goes a long way.

How to apply:

  • Use a pea-sized amount for the entire face and neck
  • Warm between fingertips, then gently smooth into the skin

When to use

  • Apply every evening as the final step in your routine
  • Use after cleansing (and after any optional serums, if desired)

FAQs

Can I keep track of my progress?

Yes. We encourage all Skin Diary patients to provide feedback and track progress each month so we can tweak and tailor your routine based on your experience and results. Our goal is to help you achieve maximum benefits with zero irritation.

How long will it take to see results?

Result timelines vary due to many factors but typically you start seeing results within 3 months of consistent use.

Why prescription grade?

The Skin Diary's freshly compounded, prescription-grade actives are up to 80x more powerful than those found over the counter. This is why your routine needs to be monitored by our team of dermatologists (and why your results will be so good).

What if I am pregnant or breastfeeding?

Due to the nature of the ingredients, our Chapters routine isn't suitable if you are pregnant or breastfeeding. However, please reach out to our team who can help with offering safe alternatives.

When will i receive my routine?

Your Chapters routine is shipped on the 1st of each month. If you'd prefer another date, our team are happy to assist and arrange an alternative date.

Why freshly compounded?

Chapters is made bespoke to you to ensure freshness (you'll find no stability issues here) and efficacy.

What ingredients will my formulation contain?

It depends on your skin type, goals and what our dermatology team believes your skin needs. Our ingredients evolve as science evolves so you'll always have first-class formulations. You can see our ingredients here.

Why a subscription?

The best results come from consistency. We recommend a minimum of 3 months to begin seeing results with continued long-term benefits. The Skin Diary has no lock ins and offers the ability to turn off auto-renew.

Do I need a consultation?

  • You do not need to have a consultation as we ask that you fill out a detailed online consultation form and upload a photo for our dermatology team to review. See the link to the Chapters questionnaire. However, if you prefer to have an online consultation, click here to book - video call.
  • NB: If you've already seen a Skin Diary clinician you don't need another consultation.

How much does Chapters cost?

Our treatment plans range from £45 to £150, depending on your needs.

Do I need a prescription from my doctor?

Chapters is a prescription product but our team of dermatologists handle all of that for you, so no need to visit your doctor.

Our Standard

Cell-to-Surface™

We believe our testing should match the ambition of the formula. 

For our products designed to drive profound, lasting changes to your skin health, we test the final formulation across three distinct dimensions before it ever reaches your routine:

  • Before After

    Tested at the Cell

    Biological Validation

    We test beneath the surface to ensure the formula actively supports your skin’s long-term structural health.

  • Before After

    Measured on the Surface

    Clinical Proof

    Clinically assessed in independent studies using advanced tools to track visible results.

  • Before After

    Perceived in the Mirror

    Consumer Validation

    Science only matters if you can see the difference. We use independent user panels to confirm our scientific research translates into real-world, visible confidence.

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LEARN MORE

A Global authority in skin ageing

Created by Prof. Chris Griffiths OBE

Professor Chris Griffiths OBE is one of the world’s most distinguished consultant dermatologists, awarded an OBE in 2018 for his globally recognised services to dermatology.

Prof. Griffiths was part of the pioneering research team that first discovered exactly how topical retinoids repair the cellular structure of aged skin and has spent decades studying the biological mechanisms of skin ageing. 

Night Repair Therapy is the culmination of this life’s work: a final formulation that harnesses his deep understanding of retinoid pathways to deliver clinical-grade repair, without the irritation.

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DEEP RESULTS TAKE TIME TO BUILD

What to Expect

1 Week

THE SURFACE RESULT

You will notice a visible softening of fine lines and a smoother surface texture. It is important to know that these early changes are primarily driven by moisturisation and barrier repair.

1 Month

The first renewal cycle

As your skin completes its first natural 28-day turnover, the biological support begins. Your skin may feel softer to the touch, without the redness or flaking that can arise from retinol.

3 Months

The Clinical Milestone

This is when our clinical trials measured a statistically significant reduction in the appearance of deeper wrinkles, alongside a visibly healthier, more vibrant complexion.

6 Months

Profound, Lasting Health

Skincare is a long-term investment. By month six, your skin’s barrier and underlying structure are consistently supported. You will maintain a resilient, healthy barrier, sustained visible firmness, and an ongoing daily defence against the visible signs of ageing.