• Night Repair Therapy
  • Night Repair Therapy
  • Night Repair Therapy
  • Night Repair Therapy
  • Night Repair Therapy
  • Night Repair Therapy
  • Night Repair Therapy
  • Night Repair Therapy
  • Night Repair Therapy
  • Night Repair Therapy
  • Night Repair Therapy
  • Night Repair Therapy
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Night Repair Therapy

Night Cream Proven to Reverse Skin Age

Reverse signs of ageing with clinically proven skin repair—without irritation.

£135.00
£135.00

  • 20x more effective than retinol
  • Boosts collagen and elastin for firmer, youthful skin
  • Repairs sun damage and restores skin barrier health
  • Developed by world-leading dermatologists
  • Gentle, irritation-free formula suitable for sensitive skin
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Born from decades of pioneering research by Professor Chris Griffiths OBE and Dr. Tamara Griffiths. With research conducted in skin biology and regenerative medicine, this powerful formulation is clinically proven to increase collagen and elastin production, resulting in youthful-looking skin.

Key Benefits

Night Repair Therapy protects, rebuilds, and restores your skin’s structure in 3 ways. 

Protect: First by protecting your skin’s healthy cells. Bilberry acts as a potent inhibitor of hyaluronidase, collagenase and elastase, which causes tissue degradation. While lycopene obtained from bio liquified organic tomato skin protects from UV-induced, photo-oxidative stress and inflammation.

Renew: The second reparative phase uses retinyl-ester and cell-communicating peptides to rebuild the cellular structure. The synergy of protective and reparative actives allows Night Repair Therapy to trigger collagen and elastin repair and deliver unparalleled results.

Restore: Night Repair Therapy is formulated to restore with carefully selected delivery mechanisms of fatty acids and humectants, Night Repair Therapy has been designed to mimic the skin’s natural oils optimising active ingredient absorption, skin moisture levels and skin barrier function.

The Evidence

How do we know it works?

Simple. It’s held to the highest standard of scientific testing. 

Double-blind, placebo-controlled clinical studies in human skin. 

Published data[2] highlighted significant increase in collagen and elastin; crucial to reversing signs of ageing. 

Manchester Patch Test Assay 

This is a rapid in vivo test that predicts an anti-ageing product’s ability to restore microfibrils in photoaged skin. In short: It shows us exactly which products can repair the skin at a structural level and improve signs of ageing.

Ingredients

Protect

Vaccinium Myrtillus Fruit Leaf Extract, Hydrolysed Tomato Skin, Niacinamide

Bilberry extract: Inhibits free radical damage

Hydrolysed tomato skin: Shields from photo-oxidative damage

Niacinamide: Maintain healthy skin during environmental exposure

Renew

Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Retinyl Palmitate

Cell-communicating peptides: Increase collagen synthesis
Retinyl-ester: Regenerates skin and promotes cell turnover

Restore

Helianthus Annuus Seed Oil, Cocos Nucifera Oil, Theobroma Cacao Seed Butter, Prunus Amygdalus Dulcis Oil, Simmondsia Chinensis Seed Oil

Medium & long chain hyaluronic acid: Moisturises the skin
Botanical oils: Retains moisture and soothes

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As seen in

Before

After

Clinically Proven Results

Clinical studies on Night Repair Therapy showed significant increases in the skin’s collagen and elastin levels—crucial to reversing visible signs of aging.

20x

More effective than retinols[1]

2x

Increase in collagen[2]

2x

Increase in fibrillin[2]

Zero

Irritation

Clinically Proven

To reduce wrinkles [3]

[1] Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-48. doi: 10.2147/ciia.2006.1.4.327. PMID: 18046911; PMCID: PMC2699641.

[2] Langton AK, McConnell JC, Cotterell LF, Halai P, Griffiths TW, Griffiths CEM, Watson REB. Restoration of collagen and elastic fibre networks following treatment of photoaged skin with Serènesse (Night Repair Therapy), a novel over-the-counter anti-ageing product. J Eur Acad Dermatol Venereol. 2022 Jan;36(1):e43-e46. doi: 10.1111/jdv.17612. Epub 2021 Aug 30. PMID: 34416056.

[3] Independently proven on 29 people over 12 weeks p value 0.0004

View Our Studies

  • CREATED BY CONSULTANT DERMATOLOGISTS

  • SCIENTIFICALLY PROVEN RESULTS

  • MADE IN THE UK

Proven Benefits in Just 12 Weeks

✔ Smooths fine lines and wrinkles for firmer, youthful skin

✔ Reduces hyper-pigmentation, age spots, and other signs of photo-ageing

✔ Deeply hydrates while improving skin elasticity and suppleness

✔ Strengthens the skin barrier to maintain healthier, more resilient skin

✔ Encourages cellular turnover for ongoing improvements in tone and texture

✔ Improves skin structural support, preventing premature skin ageing

✔ Improves skin texture by smoothing out the skins surface

How Night Repair Therapy Works

At the heart of Night Repair Therapy is a 3-step mechanism —
Protect, Renew, and Restore — that transforms your skin from the inside out.

  • 1. Protect

    Stops damage before it starts

    Antioxidants shield healthy cells from free radicals, UV-induced oxidation, and environmental stress.

  • 2. Renew

    Activates the skin's repair process

    Cell communicating peptides and retinyl ester stimulate cellular regeneration, increasing collagen and elastin for structural repair

  • 3. Restore

    Rebuilds your skin's natural barrier

    Fatty acids mimic the skin's natural oils, locking in moisture and reinforcing long-term resilience.

Key Ingredients

Created by Dermatologists, Loved by Dermatologists

  • Professor. Chris Griffiths OBE

    World Renowned Skin Researcher, Co-Creator of Night Repair Therapy

    "This repaired fibrillin to a similar level as the gold standard but uniquely it also increased collagen in the assay"

  • Dr. Tamara Griffiths

    Consultant Dermatologist, Co-Creator Night Repair Therapy

    "We set out to match the power of the gold standard treatment —without the irritation. Night Repair Therapy delivers on that"

  • Dr. Clare Kiely

    Consultant Dermatologist, Mohs Surgeon, Co-founder The Skin Diary

    "Night Repair Therapy closes the gap between cosmetic skincare and clinical science. It’s everything we stand for at The Skin Diary."

Customer Reviews

Based on 68 reviews
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J
Jo Philips
Good results

I used this for almost 10 weeks which is how long the jar lasted me. I noticed an improvement in my skin and felt it looked smoother. I didn’t get another jar immediately as it’s quite expensive so I have had a gap of a few weeks and am going to repurchase it as I did feel it made a difference to my skin.

L
Linda

This is my must have product . Love love love! Replaced my tretinoin with this it feels so nourishing

E
Erica Smith
fantastic results

I've been using the skin diary night cream for two months now and I can see a really good improvement in my skin, it's plumper especially around the mouth and I have such a nice complexion. I would highly recommend this cream

A
Anne H
Simply the best!!

I can honestly say this is the best ever product of its type that I have ever used. Definitely expensive but if you can afford it there is nothing that is in the same league for quality and effectiveness. I will never purchase a different night care scheme again.

L
Liz F
Impressive results

My skin is really sensitive so I usually stick to products that I know it can tolerate - anything with retinol/higher strength ingredients tends to make my face feel like it's on fire within a few minutes. Eye creams are the absolute worst. I purchased Night Repair Therapy with some trepidation for this reason as the price makes it an investment (however, despair at my fine lines pushed me over the edge). I have been using for around 8 weeks exactly as instructed - eye area included - and am pleased to say have experienced zero irritation and a clear improvement in skin tone/appearance. Seldom wearing foundation and have virtually stopped googling 'Botox near me' - it's that good!

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FAQs

Will Night Repair Therapy make my skin peel or dry out?

No. The formula is specifically designed to minimise irritation, including dryness or peeling. The retinyl ester used in Night Repair Therapy is a milder form of retinoid that offers all the powerful benefits without the irritation often associated with traditional retinoids.
Where can I buy Night Repair Therapy?

You can purchase Night Repair Therapy directly through our website. Click on the "Buy Now" button to start your journey to healthy, rejuvenated skin.
What type of clinical testing has been done on Night Repair Therapy?

Night Repair Therapy has undergone rigorous double-blind, placebo-controlled clinical trials in human skin. These studies demonstrated its ability to significantly increase collagen and elastin production, crucial for reducing wrinkles and improving skin firmness.
How do I use Night Repair Therapy?

Apply a pea-sized amount of Night Repair Therapy to cleansed skin in the evening, focusing on areas with visible signs of ageing.

Is Night Repair Therapy tested on animals?

No. Night Repair Therapy is cruelty-free and has not been tested on animals. Our commitment to ethical testing aligns with our goal to deliver results without compromising on quality or integrity.
How does Night Repair Therapy renew the skin?

The formula contains peptides and retinyl ester, which stimulate collagen and elastin production while promoting cellular turnover. Hyaluronic acid (in two different molecular weights) helps to maintain skin elasticity and moisture levels, providing a plump, youthful appearance.
What are the key ingredients in Night Repair Therapy?

Night Repair Therapy features a blend of peptides, retinyl ester, bilberry, hydrolysed tomato skin, two chains of hyaluronic acid. These ingredients work together to protect, renew, and restore the skin for optimal anti-ageing results.
Can I use Night Repair Therapy with other skincare products?

Absolutely. Night Repair Therapy easily integrates into your existing skincare routine or with our personalised routines: Chapters. Night Repair Therapy is best used after cleansing.

Is Night Repair Therapy suitable for sensitive skin?

Yes. Night Repair Therapy is designed to deliver powerful anti-ageing benefits without irritation, making it suitable for sensitive skin types. The unique formula combines active ingredients with soothing botanicals like bilberry and hydrolysed tomato skin to minimise risk of irritation.

How long does it take to see results with Night Repair Therapy?

You can expect to see visible improvements in your skin within 3 months of consistent use and continued improvement in the months following. Clinical studies show significant increases in collagen and elastin levels, which are key to reversing signs of ageing.
What makes Night Repair Therapy different from other anti-ageing creams?

Night Repair Therapy uses a unique three-step approach: protecting healthy cells, renewing damaged ones, and restoring the skin barrier. Unlike other retinoid products, it delivers results without irritation thanks to its carefully balanced blend of peptides, retinyl-ester, antioxidants, and advanced delivery mechanisms. It's been tested in double-blind, placebo-controlled clinical trials, ensuring its effectiveness.

I am sensitive to retinoids, will I be okay with Night Repair Therapy?

Our rigorous testing showed Night Repair Therapy to be well-tolerated for sensitive skin and retinoid sensitivity. However, everyone's skin is unique so if you're allergic to or have questions about specific ingredients, please reach out to our team who are happy to help.

Can I use Night Repair Therapy every night?

Yes, we encourage you to use it every night to see best results.

Can I use Night Repair Therapy while pregnant or breastfeeding?

Night Repair Therapy is not safe for breastfeeding due to the inclusion of retinoids in the formula.

Are all costmetic products tested on human skin?

No, many products aren't tested on human skin, which is why Night Repair Therapy is so unique.

How do I know it works?

By the rigorous testing we carry out. Night Repair Therapy has been held to the highest standard of scientific testing. Double-blind, placebo-controlled clinical studies in human skin.