DNA Repair Enzymes: The Science Behind Skin Repair with Dan Yarosh, PhD

In this episode of Skin Ageing Unlocked, Fiona Clark and Dr Clare Kiely are joined by molecular biologist Dan Yarosh, a pioneer in DNA repair enzyme research.

The conversation explores a significant shift in how we think about skincare: moving beyond protection alone, towards actively supporting the skin’s natural repair processes at a cellular level.

DNA acts as the blueprint for every function within the skin, yet it is constantly under attack from ultraviolet radiation and environmental stressors. As Dan explains, each cell experiences tens of thousands of DNA damage events every day, making efficient repair essential for maintaining healthy, functioning skin.

This episode brings together cutting-edge molecular science and clinical dermatology to explore how DNA repair enzymes work, why delivery systems are critical, and what the research tells us about their role in skin health and ageing.

Ultimately, it offers a new perspective on what effective skincare could look like in the future, one that prioritises not just protection, but repair. 

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