Pro-Helix C
Pro-Helix C
Collagen Peptide Brightening Serum
Targets skin’s lost elasticity for firmer, brighter skin.
A luxurious milky serum that goes beyond typical vitamin C. In a single morning step, discover clinically proven brightening from the first application with cellular renewal for firmer, more elastic skin. In a pH neutral formula; gentle enough for sensitive skin.
- Immediate & lasting radiance: Clinically proven to increase skin brightness.
- Visibly reduces fine lines & wrinkles: Reduction in the appearance of fine lines and wrinkles in 7 days.
- Restores skin firmness: Increase in elastic fibres in cellular testing.
- Suitable for sensitive skin: Dermatologically approved pH neutral formula.

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Pro-Helix C
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KEY BENEFITS
Brighter, More Radiant Skin
Clinically proven to deliver an immediate boost to skin brightness. 94% showed brighter skin within 7 days.[1]Reduces Fine Lines & Wrinkles
Clinically proven to reduce visible fine lines and wrinkles in as little as 7 days[2]Improves Skin Firmness & Elasticity
Human skin biopsy study showed a significant increase in elastic fibres. 87% of participants said their skin appeared firmer and more plump after four weeks of use.[3]Protects Collagen
2.4x boost in key antioxidant defence. Helping protect collagen from environmental stressors.[4]View Citations
"We have evidence of a measurable structural change within human skin, and that's where the story becomes quite different from a conventional vitamin C serum."
Dr. Clare Kiely
CONSULTANT DERMATOLOGIST
SWITCH ON MORE THAN GLOW
Proven Results
Rigorously tested across all three dimensions of our Cell-to-Surface™ standard
BEFORE
AFTER 8 WEEKS
BEFORE
AFTER 4 WEEKS
BEFORE
AFTER 8 WEEKS
BEFORE
AFTER 8 WEEKS
BEFORE
AFTER 8 WEEKS
BASELINE
PRO-HELIX C AFTER BIOPSY
SEE THE DIFFERENCE RESULTS BEYOND VITAMIN C
TESTED AT THE CELL
MEASURED AT THE SURFACE
PERCEIVED IN THE MIRROR
Pro-Helix C
1. Tested at the Cellular Level
The Manchester Patch Test Assay & Spatial Transcriptomics
The Process
Manchester Patch Test Assay:
Intra-subject controlled, double-blinded study on human volunteers with skin biopsies taken and biomarkers examined under microscope. Validated & bench-marked against prescription product.
Spatial Transcriptomics:
After the patch test, the skin biopsies from treated and untreated sites are sliced wafer-thin and placed in the Xenium machine. It tags and images the RNA for 300 genes to show which genes switched on, in which cells, and exactly where in the skin.
The Purpose
Manchester Patch Test Assay:
Rapidly models 6 months of use on live human skin.
Spatial Transcriptomics:
Provides a precise map of how the product changed skin biology at the cellular level.
The Result
- Scientifically proven to increase fibrillin deposition in human skin
- 32% higher relative P4HA2 transcript abundance in superficial fibroblasts; increased in 5/5 donors in spatial transcriptomics
- Approximately 2.4-fold higher expression of the antioxidant enzyme gene SOD3 in spatial transcriptomics.
2. Measured on the Surface
Clinical Trial
The Process
32 people have baseline professional Visioscan & Skin Gloss Metre in controlled conditions to measure wrinkle depth & brightness, images are taken before using the product, at 7 days, 28 days and 56 days. Computer-measurements are taken and compared to the baseline.
The Purpose
A good study to see if visual improvements are obtained from use of the product.
The Results
- Clinically proven to reduce the appearance of fine lines & wrinkles from day 7
- Clinically proven to deliver an immediate boost to skin radiance maintained at 56 days
3. Perceived in the Mirror
Consumer Trial
The Process
45 people are provided with the product to use for 28 days, volunteers are asked questions about their experience at 0, 7 days, and 28 days.
The Purpose
This study is useful to understand volunteers' experience from product use, while it lacks rigorous scientific credentials, it helps to ensure that a person's experience aligns with the scientific results.
The Results
- 91% experienced brighter skin within 7 days.
- 87% said skin appeared firmer and more plump after use.
- 73% said they would switch from their current vitamin C product.
Why Switch From Your Current Vitamin C Serum?
Pro-Helix C goes beyond glow alone
Improves Brightness L-Ascorbic Acid (Gold Standard): YesPro-Helix C: Yes
94% of Pro-Helix C clinical trial participants showed brighter skin within 7 days
Protects Collagen L-Ascorbic Acid (Gold Standard): YesPro-Helix C: Yes
Vitamin C contributes to normal collagen formation for the normal function of the skin.
Provides Antioxidant Protection L-Ascorbic Acid (Gold Standard): YesPro-Helix C: Yes
Vitamin C is the most plentiful antioxidant in human skin. It protects against environmental stressors by donating electrons to neutralise free radicals. Pro-Helix C takes this further showing a 2.4x boost in key antioxidant defence signals created by the body.
Increases Elastic Fibres for Visibly Firmer Skin L-Ascorbic Acid (Gold Standard): NoPro-Helix C: Yes
In a human skin biopsy study, Pro-Helix C showed a significant increase in elastic fibres, namely fibrillin.
Formulated for Sensitive Skin L-Ascorbic Acid (Gold Standard): NoPro-Helix C: Yes
Pro-Helix C uses a combination of THDA vitamin C and acetyl-zingerone to create a lipid-soluble form of vitamin C that is stable. This means we have been able to formulate the product at a neutral pH with no added fragrance, which doesn't cause irritation to sensitive skin and doesn’t block pores.
Powered by Collagen-Signalling Peptides L-Ascorbic Acid (Gold Standard): NoPro-Helix C: Yes
Pro-Helix C combines two peptides: one that signals collagen repair and another that switches on the growth-factor pathway directly for firmer, more elastic skin.
More Than Vitamin C.
15% THDA Vitamin C
The lipid-soluble form. Highly stable, well tolerated, and it penetrates properly rather than sitting on the skin's surface.
4.5% Dual Peptide Complex
Two complementary signals telling your skin to build new collagen - not just protect the old.
0.5% Acetyl Zingerone
The bodyguard. Most antioxidants are depleted the moment they neutralise a free radical. This one keeps going; protecting your collagen for hours after you apply it.
View the full INCI
Aqua, Tetrahexyldecyl Ascorbate, Glycerin, Dipropylene Glycol, Simmondsia Chinensis (Jojoba) Seed Oil, Dicaprylyl Ether, Maltodextrin, Glycine Soja (Soybean) Seed Extract, Acetyl Zingerone, Palmitoyl Tripeptide-5, Collagen Amino Acids, Squalane, Tocopheryl Acetate, Sodium Hyaluronate, Lecithin, Ethylhexylglycerin[1], Sorbitan Isostearate, Hydroxyethyl Acrylate/Sodium, Acryloyldimethyl Taurate Copolymer, Sodium Acrylates Copolymer, Polysorbate 60, Phenoxyethanol, Citric Acid
DEEP RESULTS TAKE TIME TO BUILD
What to Expect
1 Week
Within 1 week, your skin will appear more radiant with a healthy-looking glow.
1 Month
By 1 month of continued use, you will start to see early visible improvements. Your complexion appears brighter, more even and refreshed. Daily antioxidant support helps defend against environmental stressors that can contribute to dullness and uneven skin tone.
3 Months
By 3 months your skin is building resilience so it feels firmer and smoother. Fine lines appear less noticeable, while the complexion looks visibly plumper and more luminous.
6 Months
As 6 months of use come around, you'll feel and see the full cumulative effects: skin appears noticeably firmer and more elastic, with improved overall radiance and more even-looking tone. Your complexion looks healthier, brighter and more youthful.
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FAQs
How to Use
Apply evenly to the whole face every morning before your sunscreen.
What texture is it?
Pro-Helix C is a lightweight, fast-absorbing milky serum texture that layers seamlessly with sunscreen and makeup.
Does it cause irritation?
No. Pro-Helix C has been dermatologically tested and approved. Clinically proven non-comedogenic. Suitable for even sensitive skin.
How long will it take to see results?
Consistency is key with any topical skincare product. So it's important to commit to daily use for best results.
Within 1 week, your skin will appear more radiant with a healthy-looking glow.
By 1 month of continued use, you will start to see early visible improvements.Your complexion appears brighter, more even and refreshed. Daily antioxidant support helps defend against environmental stressors that can contribute to dullness and uneven skin tone.
By 3 months your skin is building resilience so it feels firmer and smoother. Fine lines appear less noticeable, while the complexion looks visibly plumper and more luminous.
As 6 months of use come around, you'll feel and see the full cumulative effects: skin appears noticeably firmer and more elastic, with improved overall radiance and more even-looking tone. Your complexion looks healthier, brighter and more youthful.
- 5 stars: 40 (95%)
- 4 stars: 2 (5%)
- 3 stars: 0 (0%)
- 2 stars: 0 (0%)
- 1 star: 0 (0%)
I’ve been using skin diary day and night creams for the last 9 months. Recommend to me by my skin Aesthetic professional. Was so happy to see the vitamin C product - pro helix C was becoming available. This was the product I felt was missing from my skin regime.
I have used the 3 day pro-helix trial and found this to feel lovely on my skin no irritation whatsoever just an extra glow which is just what I want from my skin care products. This will definitely will be part of my daily routine. Thank you ☺️
A beautiful addition to my skincare routine! ⭐⭐⭐⭐⭐
Having used The Skin Diary’s Night Repair Therapy for two years, I was really excited to try Pro-Helix C, and it certainly hasn’t disappointed!
The texture is gorgeous — silky, lightweight and luxurious. It absorbs beautifully into my skin without feeling greasy or sticky, leaving it feeling hydrated, smooth and looking wonderfully radiant.
As I’m getting older, I’m increasingly conscious of maintaining my skin’s firmness, elasticity and overall health, so I particularly love the science behind this product.
It’s a lovely addition to my morning routine and complements my much-loved Night Repair Therapy perfectly.
Another beautifully considered product from The Skin Diary. I’m excited to see the longer-term results!
I received a 3 day sample of this with my night therapy order and I loved it so much that I had to buy the full size product. It's so nice to apply, a little goes a long way, and my skin is already soft and radiant, I thoroughly recommend it!
I received a three day sample of Pro-Helix C, and as a regular user of high quality skincare products, I was seriously impressed with this serum. The immediate glow that Pro-Helix C provided was seriously impressive. I would definitely purchase this product after my trial, and I would wholeheartedly recommend it to others.
I received a tester of the Pro Helix C Collagen Peptide Brightening Serum, and the first thing I noticed was the incredible glow it left on my skin — just wow! ✨ It absorbs beautifully and sinks into the skin perfectly without feeling heavy. While I can’t comment on the long-term effects just yet, my first impression is really positive, and I would definitely recommend giving this product a try!
The Vitamin C cream is lovely and even my sensitive, rosacea/prone skin feels better since starting to use it. Great service, fast delivery.
Lovely product. Smells fabulous and glides on to the skin beautifully. I would definitely buy again.
I have been using this for about 3 weeks and I can definitely see that my skin looks brighter. I am very happy with it and use every day before my skin diary daily moisturiser which I also love.
I received the 3 day sample and am very impressed. I don’t normally purchase products with a fragrance as I have sensitive skin. However I have had no reaction and have purchased the full size to use along with my age defence day and night repair creams. Highly recommend
One of the nicest serums I’ve used. After only one week I can already see a difference in the brightness of my skin. It goes on really nicely under my sun cream which I have to use daily so that’s great. Beautiful packaging too. And it leaves your skin smelling wonderful.
A really lovely serum that absorbs well and sits under the SPF day moisturiser perfectly. It has a wonderful aroma too! I didn’t hesitate in purchasing this after the sample and feel my skin already looks brighter. Well done Skin Diary!
This serum is lovely my skin is glowing love it
I have used many Vitamin C serums over the years, some can be harsh, some don't sit well under your moisturiser and SPF. Pro-Helix C is light but effective, it leaves your skin hydrated and brightened and my other products layer nicely over the top.
I received a sample of this and I really am astounded by the glow it gives. Such an amazing result in such a short space of time - three applications. I would definitely recommend this and would also purchase it. Just wonderful 🙌🙌
I was grateful to receive a free sample of Pro- Helix which I applied in the morning before the moisturiser for 3 days. It was lovely to apply and absorbed into my skin easily. I waited a short while before applying the moisturiser. My skin instantly had the appearance of looking brighter, although it is too soon to say whether it has improved the appearance of fine lines. I have used the Duo set for a while and love how they make my skin feel and look, with no irritation. Although I love the simplicity of using 2 products, I am keen to add this 3rd product to see if it enhances what I already use over a longer period of time.
Pro-Helix C . I received the 3 day sample and was very impressed, lovely texture and absorbed quickly into the skin .Will be adding this to my routine ❤️
I received the free sample & loved the product immediately - it is a beautiful product to use & the skin feels better even after using the sample.
I’ve given it 4 stars because I’ve only used a sample over 3 days. It definitely brightened my skin and the texture after using felt really nice. I already use the night repair and day moisturiser so what I would say is that adding this in makes the routine very expensive. It would be nice to see bundle offers or something similar. Overall it is a nice product and I would probably consider purchasing.
As an avid fan of Skin Diary’s Age Defense, I was really chuffed to receive the 3-day free samples of the new Vit C product. Although too early to see any real progress yet, the cream was lovely to apply, quick to absorb & had a lovely faint aroma of fudge - never a bad thing in my opinion! It didn’t pill & laid a real smooth surface for my Age Defense cream. A great addition to a simple but effective skin routine, thank you.
As an avid fan of the Age Defence cream, I was really chuffed to receuv
I received a sample of this and I really liked it. It had an immediate brightening effect and the texture is beautiful. I will be buying the full sized product.
I was lucky enough to receive a 3-day sample of the Vitamin C to try, and it certainly didn’t disappoint! Whilst I think it’s too soon to see the full benefits, I absolutely loved how smooth and glowing my skin looked and felt after using it. It also layered perfectly between cleansing and applying my Skin Diary day cream, with no pilling at all.Since introducing both the night cream and day cream, I’ve simplified my skincare routine, and this feels like a lovely little addition. My skin feels great, and I’m looking forward to seeing the longer-term benefits!
Having used the 3 day sample trial I would give 5stars. It was very easy to rub in and felt really good once absorbed. It gave an instant glow to my skin and sat nicely under my usual moisturizer and sunscreen with no 'pithing'. I can experience sensitive skin, especially with vitamin C products so I loved the fact that high performance is paired with zero irritation. I'll be changing my vitamin C to this product
O tried the vitamin c sample that was sent to me and immediately my skin felt and looked glowing so will definitely be purchasing this for my morning skincare routine
I was surprised when I got the three day sample that it would have any effect in such a short period .. but I have noticed a smoothness and brightness in my skin will definitely invest in this and see what a sustained period of use will do
As a big fan of Skin Diary products, I was delighted to try a sample of the new vitamin C product. It was lovely to apply, very smooth and left a lovely glow on my skin. Looking forward to adding it to my regular Skin Diary routine.
Amazing product. It feels and smells great. Very light and is absorbed instantly. I’ve only been using for a very short time but I’m sure I can see a difference in my complexion already. Lovely
I really like this serum.. it’s light, easily absorbed and non sticky like other brands. I am only using it a short time but I can already feel the difference.
I have just started using new pro helix. It has a beautiful light texture and is easily absorbed. I love all the skin diary products. It has become my regular night and morning routine
Vitamin C is so important to the skin and this new product looks to deliver exactly what it says.
Thanks skin diary.